RNA Details
Disease Name
carcinoma hepatocellular
Tissue
liver
RNA Symbol
mir-148a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR
Target
IKB KINASEA; NUMB
Pathway
NOTCH SIGNALING PATHWAY
PubMed ID
Title
Differentiation therapy for hepatocellular carcinoma: Multifaceted effects of mmiR-148a on tumor growth and phenotype and liver fibrosis
Year
2016
Function
"Mir-148a is an inhibitor of ikb kinase a ; Numb ; Notch pathway and a hepatocyte differentiation inducer, and its expression disorder promotes the development of hcc. Differentiated targeted therapy may be a promising strategy for the treatment and prevention of hcc."